NEUROVisor

Сlinical EEG system

OVERVIEW

Based on NVX amplifiers, a clinical EEG system NEUROVisor has been developed for use in functional diagnostics rooms, medical departments of multidisciplinary and neurological hospitals, health centers, clinics and research institutes.

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SOFTWARE

EEG amplifier NeoRec 21 supports research software NeoRec and clinical software NEUROvisor.

NeoRec software

NeoRec is a PC software designed for experiment planning and for recording EEG and other biomedical signals during scientific or medical research, including Evoked Potentials preprocessing.

Record files can be saved in different formats (EDF+ 16 bit, BDF+ 24 bit, GDF 32 bit) or transmitted online via stream LSL (Lab Streaming Layer) for analyze by third party software, as MATLAB / EEGLAB, OpenViBE etc.

SDK for software development for PC and mobile applications is provided by the manufacturer upon request.

NEUROvisor software

NEUROVisor is a clinical EEG software which is available on PC and as mobile application.

Software NEUROVisor is a friendly one button solution, which provides standard montages and examination scenarios according to IFCN guidelines, automatic or semi-automatic examination procedure with voice prompts, automatic artifact rejection using ICA method, automatic generation of reports with manual editing capability.

Quantitative EEG presented by amplitude-frequency analysis of the main EEG rhythms, spectral analysis (charts and maps), independent component analysis.

SPECIFICATION

EEG amplifier

	NVX24	NVX36	NVX52
EEG channels	24	32	48
Channels of sensors	–	4 galvanic isolated from EEG
Synchronization channels	1 / 1	9 / 1
Display	none	Graphic OLED 3.2", 256 x 64 px
Connector type for connecting EEG cap with common connector	DB‑25F	DB‑25F, KEL40M (KEL 8830E‑040)	KEL50M (KEL 8830E‑050)
Type of connectors for connecting EEG electrodes	TouchProof 1.5 mm (DIN 42 802‑BU)
Connector type for sensors	none	5‑pin Binder
Sync connector type	3.5 stereo plug	3.5 stereo plug, DB‑9M
Input dinamic range of EEG channels	not less then ± 400 mV
Common-mode signal attenuation coefficient	> 110 dB
Common mode input impedance at 3 Hz	> 100 MOhm (DC)
Noise of EEG channels	< 0.9 µV pk-pk @ 0.1..30 Hz
Electrode impedance measurement range	1 to 120 kOhm (±10%) @ 30 Hz
EEG test signal	square 200 µV (±1%), 1 Hz
Input dinamic range of sensor channels	–	0–4 VDC
Input impedance of sensor channels	–	≥ 20 MOhm (DC)
Noise of sensor channels	–	< 15 µV pk-pk @ 0.5..30 Hz
Control and power				from PC via USB type B interface
Supply voltage	5 VDC (±5%)
Consumption current	< 450 mA
Powering of sensors	–			from amplifier, 5 VDC (±5%)
Galvanic isolation	reinforced, according to IEC 60601-1
Galvanic isolation of synchronization channels	Reinforced isolation from all channels, test voltage 4000 V, 50 Hz (1 min). The triggers are located on the PC side. (Refer to PC circuit).
Digitalization	24 bit, 6th order delta-sigma modulator with 64x oversampling, one converter per each channel
Type of amplifier input stages	DC amplifiers
Sampling rate				250, 500, 1000, 2000, 5000 Hz (for all channels); 10000 Hz up to 24 mono- or bipolar channels; 50000 Hz up to 4 mono- or bipolar channels;
Lower cutoff frequency at -3 dB	0 Hz (DC, software filtering)
Upper cutoff frequency at -3 dB (depending on sample rate)				75 Hz (-3dB @ 250 Hz); 175 Hz (-3dB @ 500 Hz); 300 Hz (-3dB @ 1000 Hz); 500 Hz (-3dB @ 2000 Hz); 1650 Hz (-3dB @ 5000 Hz); 4900 Hz (-3dB @ 10000 Hz); 16000 Hz (-3dB @ 50000 Hz)
TTL levels of input channels synchronization				low level Uil > +0.8 V, Iil > -2.1 mA high level Uih > +3.5 V, Iih > -0.1 mA
Output TTL levels of synchronization channels				- low level Uol < +0.4 V, Iol < -1.6 mA - high level Uoh > +2.8 V, Ioh > 0.5 mA By default, output trigger channels are High.
Synchronization channel mode				Synchronously with the issued channel readings; Accuracy ±0.5 / reading
Mode indication				Mode indicator
Indication of operating parameters	–	on the amplifier display
Dimensions (LxWxH)	200×155×40 ±5mm
Weight	545 ±50 g	615 ±50 g	635 ±50 g

Photic stimulator FSS4

Number of LEDs	32 pcs.
Brightness of light stimuli	10-100% in 1% increments
Color of lighting	white
Frequency of generation of light stimuli	1-60 Hz with a resolution of 1 Hz with an allowable deviation of the following frequency of photostimuli no more than ±10%
Maximum brightness of light signals	≥ 2000 cd/m²
Light flow	≥ 1100 lm
Angle of view	±15° from central axis direction
Sync connector type	3.5 stereo plug
Control and power	from PC via USB interface 5 VDC (±10%) Current up to 400 mA
Mode indication	Mode indicator
Dimensions (LxWxH)	114×76×35 ±5 mm
Weight	145 ±10 g

Software module Neurovisor

Parameter	Value
Age groups	infants and children (0‑10 years) adults and teenager from 10 years
Working mode	EEG acquisition and automatic report generation, EEG analysis and report editing
Scenario types	built-in (not editable); custom (customizable)
Built-in scenarios	Express (5 stages / 5 min) (default) Standard (6 stages / 15 min 20 s) Extended (6 stages / 34 min 20 s)
Number of stages in the scenario	from 1 to 10
Types of stages	Background EEG, Eyes-opened test, Eyes-closed test, Rhythmic photostimulation test, Audiostimulation test, Hyperventilation test
Duration of stages	from 20 s to 20 min
The number of sub-stages in the photic stimulation stage	from 1 to 100
Flashing at photic stimulation sub-stage	from 0 to 60 Hz
Duration of photic stimulation sub-stage	from 3 to 60 s
Transition to next stage of EEG recording	automatic (by default), manual
Patient voice instruction at acquisition time	when choosing automatic transition to the next stage
Acquisition management	Pause; add 1 min to current stage; go to next stage
Number of EEG channels	from 1 to 160
Build-in EEG montages	bipolar and with references A1A2, Cz, Av (average)
Re-montage during analysis of EEG	possible
EEG electrodes impedance quality level (impedance borders default)	good (< 40 kOhm), average (from 40 to 80 kOhm), bad (> 80 kOhm), no contact
Regulated borders of EEG electrodes impedance quality	good – average, average – bad
Sampling rate	500 Hz (default), 2000 Hz, 5000 Hz
HPF EEG cannels at -3 dB	0.016 Hz, 0.05 Hz, 0.5 Hz (default), 1 Hz, 2 Hz, 3 Hz Butterwort 1st order
LPF EEG cannels at -3 dB	15 Hz, 30 Hz, 70 Hz (default), 100 Hz, 250 Hz, 500 Hz, 1000 Hz Butterwort 1st or 4st order
Power line rejection filter of EEG channels; base / 2d harmonic	off, 50/100 Hz (default), 60/120 Hz
Speed	7.5 mm/s, 15 mm/s, 30 mm/s (default), 60 mm/s, 100 mm/s, 150 mm/s, 500 mm/s, 1000 mm/s
Gain of EEG channels	12.5 µV/cm, 25 µV/cm, 50 µV/cm, 70 µV/cm (default), 100 µV/cm, 200 µV/cm, 500 µV/cm, 1000 µV/cm
ECG bipolar leads	off (default), 1 lead, 2 leads
Type of ECG leads	I standard, II standard
HPF ECG channels at ‑3 dB	0.05 Hz (default), 0.1 Hz, 0.5 Hz
LPF ECG channels at ‑3 dB	35 Hz, 70 Hz, 150 Hz (default)
Power line rejection filter of ECG channels; base / 2d harmonic	off, 50/100 Hz (default), 60/120 Hz
Gain of ECG channels	5 mm/mV, 10 mm/mV (default), 20 mm/mV
Heart rate measuring range by ECG	30‑250 BPM
Heart rate measuring tolerance by ECG	±2 BPM
EMG bipolar leads	off (default), 1 lead, 2 leads
HPF EMG channels at ‑3 dB	1 Hz (default), 3 Hz, 10 Hz
LPF EMG channels at ‑3 dB	70 Hz, 150 Hz (default)
Power line rejection filter of EMG channels; base / 2d harmonic	off, 50/100 Hz (default), 60/120 Hz
Gain of EMG leads	automatic gain control
Passband of PPG channel at ‑3 dB	from 0.5 to 70 Hz
Gain of PPG channel	automatic gain control
Passband of breathing channel at ‑3 dB	from 0.01 to 8 Hz
Gain of breathing channel	automatic gain control
Passband of GSR channel at ‑3 dB	from 0.01 to 8 Hz
Gain of GSR channel	automatic gain control
Passband of moving channel at ‑3 dB	from 0.5 to 70 Hz
Gain of moving channel	automatic gain control
Video recording channels	up to 2 channels
Video recording frame rate	not less than 25
Video recording frame resolution	not less than 640×480 px
Video playback frame size	small 64×48 mm (by default), big 96×72 mm
Video playback and EEG synchronization at analyze mode	< 0.5 s (500 ms)
Length of EEG segment for automatic analysis	from 10 s to 6 min (100 s by default)
Possibility to change EEG segment for automatic analysis	at analyze mode
EEG amplitude threshold for artifact detection	from 60 to 1000 μV (150 μV by default)
EEG amplitude threshold for low wave (up to 1 Hz) artifact detection	from 10 to 1000 μV (150 μV by default)
EEG amplitude threshold for high wave (more than 30 Hz) artifact detection	from 10 to 1000 μV (150 μV by default)
Spectral EEG bands for analyzing	Delta 1.5...4 Hz, Theta 4...7.5 Hz, Alpha 7.5...14 Hz, Beta‑1 14...20 Hz, Beta‑2 20...30 Hz, Gamma 30...40 Hz
Moving windows types for EEG spectral power calculations	Hann (by default), Rectangle, Hamming
Moving windows length for EEG spectral power calculations	1 s, 2 s, 4 s (by default), 8 s, 16 s
On screen manual measuring of times and amplitudes	tolerance not worse than 5% for length of segment more 20 mm
Automatic text conclusion of EEG for each scenario stage	On base of automatic measuring amplitudes and frequencies EEG waves and EEG waves classification
Automatic text conclusion of EEG editing	at analyze mode
Automatic removal of eye artifacts	yes, at “eyes open” stage
Manual noise/interference removal	in the analysis mode, by the method of independent components
Report file format	PDF 1.4 according to ISO 32000‑1
Report pages size	A4 210×297 мм (by default), Letter 215,9×279,4 mm
EEG export format	EDF+
Export format of EEG text conclusion and spectral data	XLS (Excel)
Recommended EEG amplifiers	NVX24, NVX36, NVX52, NVX36T, NB2-EEG16 (MCS), actiChamp Plus C (Brain Products) Compatibility with other amplifiers, check with the manufacturer
Recommended photic stimulators	FSS4 (MCS)
Recomended sensors	Photoplethysmographic probe FPSens Thermistor-based breathing sensor TRSens Galvanic skin response sensor GSRsens Moving sensor AxSens
Methodology	1 Guidelines for carrying out of routine EEG of neurophysiology expert board of russian league against epilepsy. Epilepsy and paroxysmal conditions. №4/8. 2016;8(4):99-108. (In Russ.) 2 Chapter 1.1 The ten‑twenty electrode system of the International Federation // Recommendations for the Practice of Clinical Neurophysiology: Guidelines of the International Federation of Clinical Physiology (EEG Suppl. 52) 3 Guideline 6: A Proposal for Standard Montages to Be Used in Clinical EEG // American Clinical Neurophysiology Society, 2006 4 Seeck M, Koessler L, Bast T, Leijten F, Michel C, Baumgartner C, He B, Beniczky S. The standardized EEG electrode array of the IFCN. Clin Neurophysiol. 2017 Oct; 128(10): 2070‑2077 5 Jasper HH. The ten‑twenty electrode system. Electroencephalogr Clin Neurophysiol 1958; 16:371‑5. 6 Guideline One: Minimum Technical Requirements for Performing Clinical Electroencephalography // American Clinical Neurophysiology Society, 2008 7 Guideline Two: Minimum Technical Standards for Pediatric Electroencephalography // American Clinical Neurophysiology Society, 2006 8 JJG 954- 2000 Verification Regulation of Digital electroencephalogram mapping & brain electric activity mapping // Chinese Standard
Software version	1.4

NVX 24

24 EEG channels, Clinical EEG

DB25 connector for EEG cap

NVX 36

32 EEG channels, 4 AUX channels for probes, OLED display, Clinical EEG, EP & ERP

DB25 connector, KEL40 connector for EEG cap

NVX 52

48 EEG channels, 4 AUX channels for probes, OLED display, Clinical EEG, EP & ERP

KEL50 connector for EEG cap

ACCESSORIES

Wide range of EEG accessories MCScap are designed for NeoRec amplifiers. Different models of electrode caps with preinstalled Ag/AgCl sintered electrodes are covered all needs: from standard gel solution up to dry solution.

Textile caps in 12 sizes for the heads from 24 cm up to 66 cm circumference. Elastic material provides the most comfortable fit of the electrodes and the right positions without additional adjustment.

The material does not allow the gel or paste to dry out under electrodes fast. Marked holes for electrodes. Big holes for the opportunity to push the hair and prepare the skin for examination.

Reusable passive electrodes MCScap are based on high-quality Ag/AgCl sintered sensors which guarantee a high quality signal, a long-term stable electrical contact, a low noise reference electrode, a minimum electrode polarization, an excellent low frequency response.

SET INCLUDES

EEG amplifier NVX with 5m USB cable;
photic stimulator with 5m USB cable;
EEG electrode cap MCScap;
2 leads ECG cable with electrodes;
software license NEUROVisor;
plastic box, user manual.

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OVERVIEW

SOFTWARE

NeoRec software

NEUROvisor software

SPECIFICATION

NVX 24

NVX 36

NVX 52

ACCESSORIES

SET INCLUDES

SET INCLUDES

VIDEO

PHOTO

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NEUROVisor